Pharmacokinetics
Celerion’s scientists have extensive small and large molecule PK expertise.
Our scientific teams have decades of experience developing and validating PK assays for preclinical and clinical sample analysis across a wide range of therapeutic modalities and sample matrices. Celerion’s GxP compliant laboratories are equipped with the latest instrumentation to enable us to offer custom solutions to our clients for accurate and reliable measurements of your therapeutic.
Celerion’s LC-MS services for small molecule PK analysis
We boast one of the earliest established LC-MS laboratories in the industry, making us the go-to experts for small molecule PK work for decades. We continuously invest in new technologies to ensure we maintain a full suite of top-of-the-line instrumentation including:
- SCIEX QTRAP 7500+
- SCIEX QTRAP 6500/6500+
- SCIEX QTRAP 5500
- SCIEX API 4000, 5000
Celerion’s bioanalytical services for large molecule PK analysis
As a global leader in large molecule PK services, Celerion has an extensive list of capabilities that we leverage to provide regulated PK assay development, validation, and sample analysis for large molecule therapeutics including:
- ELISA
- MSD/ECLIA
- RIA
- SIMOA
- AlphaLISA
- Flow Cytometry (Cell Therapy)
- qPCR (Cell and Gene Therapy)
Celerion’s support for dose escalation, PK modeling, and data analysis.
With our bioanalytical labs routinely supporting phase I studies at Celerion’s early-phase clinical research facilities, we have the streamlined sample analysis and data processing systems in place to meet rapid turnaround times for dose escalation and decision making. In addition, we have a dedicated team of clinical pharmacologists with deep expertise in PK data assessment, including non-compartmental and compartmental PK analyses. See our full analysis services here.
